Mirada Medical collaborators presented PET/MRI research at the annual Society of Nuclear Medicine and Molecular Imaging (SNMMI) meeting held June 8 to June 12 in Vancouver.

David Townsend, director of the A*STAR-NUS Clinical Imaging Research Centre (CIRC) in Singapore, presented a paper entitled “Initial results of the assessment of PET/MR compared to PET/CT for diagnosis and staging of malignant disease” by Dr. Yan et al. of CIRC and National University Hospital, Singapore. This work is a comparative analysis of the image quality and quantification accuracy of hardware PET/MRI and PET/CT, a highly relevant topic of current interest in the field. Advanced quantification features and accurate deformable registration in Mirada PET/MRI software allowed the quantification of regions-of-interest simultaneously in both the PET/MRI and PET/CT of the same patient.
 
Another quantification analysis is presented in the work of Dr. Thomas Klausen et al. of Rigshospitalet, Denmark, entitled “Image distortions and bias from dental restorations in PET/CT- and PET/MR-imaging.” In this work, Mirada’s support for multiple studies and multiple sequences enabled the analysis of artifacts arising from dental fillings on image quality and quantification on hardware PET/MRI and PET/CT.
 
Mirada’s software for PET/MRI is an alternative to hybrid scanners and is based on deformable registration between the PET-CT and MRI to perform the fusion. A high-quality registration is critical for effective fusion between PET/CT and MRI. Mirada’s deformable registration algorithm is the subject of another paper by Dr. Martin Lodge et al. of Johns Hopkins University entitled “Combined PET/CT/MRI of the pelvis using software registration.” This work investigates the accuracy of the deformable registration between the CT and MR in the pelvis.